Cancer immunotherapies
by design

iTeos Therapeutics is pioneering the discovery and development of highly differentiated immuno-oncology therapeutics for patients.

At iTeos, we are specializing in targeted immunotherapies for people living with cancer.

We leverage our deep understanding of the tumor microenvironment and immunosuppressive pathways to design novel product candidates with an aim to improve the clinical benefit of oncology therapies.

Our two clinical stage programs, EOS-448 and Inupadenant, were designed with the aim of having best-in-class properties. We are moving rapidly into late stage clinical trials to explore the full potential of our science.

cancer patient wearing headscarf

Our pipeline

Our efforts are targeting various cancer indications using our drug candidates either in monotherapy or in combination with additional drugs, as well as in intraportfolio combinations.


Phase 1

Phase 2a




+ dostarlimab | Solid Tumors

Phase 1, dosing

+ dostarlimab | 1L NSCLC PDL1 high

Registration-directed, non-dosing

+ dostarlimab | HNSCC

Registration-directed, non-dosing

+ dostarlimab | Undisclosed

Registration-directed, non-dosing

+ dostarlimab + CD96 | Solid Tumors

Phase 1, non-dosing

+ dostarlimab + Inupadenant | Solid Tumors

Phase 1, non-dosing

+ Inupadenant | PD-1 Resistant Melanoma

Phase 1, dosing

Monotherapy/+ iberdomide | Relapsed Refractory Multiple Myeloma

Phase 2a, dosing


Monotherapy | Evaluating Patient and Indication Selection Biomarkers

Phase 2, dosing

+ pembrolizumab | PD-1 Resistant Melanoma

Phase 2, dosing

+ chemotherapy | Post-IO mNSCLC

Randomized, non-dosing


IND Enabling Studies

Preclinical, dosing

Studies with dark backgrounds are dosing patients. Studies with light backgrounds have not yet dosed patients.

There has never been a better time to work at iTeos.

As a leading clinical-stage biotech, our innovative science-driven work is fascinating and potentially lifesaving.

Whether it is working in our laboratory or in our offices, you will help people live healthier lives. You will find yourself on the forefront of science, within a high-tech environment where no two days are the same.

scientist working in a lab

Latest press releases

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