Cancer immunotherapies
by design™
iTeos Therapeutics is pioneering the discovery and development of highly differentiated immuno-oncology therapeutics for patients.
At iTeos, we specialize in targeted immunotherapies for people living with cancer.
We leverage our deep understanding of the tumor microenvironment and immunosuppressive pathways to design novel product candidates with an aim to improve the clinical benefit of oncology therapies.
Our two clinical stage programs, belrestotug (EOS-448) and EOS-984, were designed with the aim of having best-in-class and or first-in-class properties. We are moving rapidly into late stage clinical trials to explore the full potential of our science.
As a responsible company, we are committed to building Environmental, Social and Governance (ESG) principles into how we operate to create sustainable value for society and all of our stakeholders.
Our pipeline
Our efforts are targeting various cancer indications using our drug candidates either in monotherapy or in combination with additional drugs, as well as in intraportfolio combinations.
The following information provides an overview of our dynamic pipeline of cancer therapy development. Studies underway are grouped by our primary drug therapies, and listed out by combination with other treatments. Indications for each combination under study, along with the current and planned phases of each study, are included.
iTeos drug trials move through five phases:
Discovery
Preclinical
Phase 1
Phase 2
Phase 3
iTeos drug trials move through five phases:
Discovery
Preclinical
Phase 1
Phase 2
Phase 3
Following is a list of drug combinations currently under study with:
Belrestotug (EOS-448)
as well as the indication for each.
drug combo and indication:
+ dostarlimab | 1L NSCLC PDL1high | GALAXIES LUNG-301
status of study phases:
Phase 3, planned
drug combo and indication:
+ dostarlimab | 1L NSCLC PDL1high | GALAXIES LUNG-201
status of study phases:
Phase 2, active trial ID GALAXIES-LUNG-201
drug combo and indication:
+ dostarlimab + CD96 | 1L HNSCC PDL1+ | GALAXIES H&N-202
status of study phases:
Phase 2, active trial ID GALAXIES-H&N-202
drug combo and indication:
+ dostarlimab | 1L HNSCC PDL1high / low | TIG-006
status of study phases:
Phase 2, active, trial ID TIG-006
drug combo and indication:
+ dostarlimab + chemotherapy | 1L mNSCLC | TIG-006
status of study phases:
Phase 1, active, trial ID TIG-006
drug combo and indication:
+ dostarlimab + CD96 | Advanced Malignancies | NCT03739710
status of study phases:
Phase 1, active, trial ID NCT03739710
drug combo and indication:
+ dostarlimab + PVRIG | Advanced Malignancies | NCT05277051
status of study phases:
Phase 1, active, trial ID NCT05277051
Following is a list of drug combinations currently under study with:
EOS-984
as well as the indication for each.
drug combo and indication:
Monotherapy | Advanced Malignancies
status of study phases:
Phase 1, planned
Studies with dark backgrounds are active. Studies with light backgrounds are planned.
There has never been a better time to work at iTeos.
As a leading clinical-stage biotech, our innovative science-driven work is fascinating and potentially lifesaving.
Whether it is working in our laboratory or in our offices, you will help people live healthier lives. You will find yourself on the forefront of science, within a high-tech environment where no two days are the same.
Latest press releases
iTeos Therapeutics Presents Interim A2A-005 Clinical Trial Data, Translationa…
– Inupadenant + carboplatin/pemetrexed in Phase 2 A2A-005 trial demonstrated a 63.9% overall response rate (ORR) and a median PFS…
iTeos to Participate in Upcoming Investor Conferences
WATERTOWN, Mass. and GOSSELIES, Belgium, Nov. 26, 2024 (GLOBE NEWSWIRE) — iTeos Therapeutics, Inc. (Nasdaq: ITOS), a clinical-stage biopharmaceutical company…
